Have been involved in several meetings to determine and evaluate such signals. See below a bare outline from MIT/Sloan. May sound simplistic but there is much more at the link to flesh it out. This is more of a risk analysis checklist starting point to consider. There are a number of good industry and specific examples at the link.
Three Signals Your Industry is About to Be Disrupted
By Megan Beck and Barry Libert in MIT/Sloan
Sign #1: Your Industry Has Significant Regulatory Burdens
Sign #2: Your Customers Have to Work at Managing Their Costs
Sign #3: Your Customers’ Experience Isn’t Positive — or Even Neutral ... "
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