Tool Helps to Better Understand High-Mutating Viruses, Including COVID-19
Los Alamos Reporter, March 8, 2022
Scientists at the U.S. Department of Energy's Los Alamos National Laboratory (LANL) have developed FEVER, or Fast Evaluation of Viral Emerging Risks, a computational tool for detecting and investigating high-mutating viruses. Researchers use FEVER to design flexible measurement assays that concurrently identify whole classes of viruses for bio-surveillance, accurately diagnose an outbreak strain, and type mutations to find variants impacting public health. "We applied FEVER to COVID-19 and showed that we can indeed perform both highly specific SARS-CoV-2 diagnostics in 100 clinical samples while performing mutation typing for spike variants all at the same time," said LANL's Jessica Kubicek-Sutherland. ... '
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