Insights into Brain Functions
STANN Reveals Insights Into How the Brain Functions
Baylor College of Medicine, Ana Maria Rodriguez, December 21, 2021
Baylor College of Medicine (BCM)'s Dr. Abul Hassan Samee and colleagues developed the Spatial Transcriptomics cell-types Assignment using Neural Networks (STANN) model to obtain novel insights into brain function. Samee said the team applied STANN and other computational techniques to brain datasets of the mouse olfactory bulb, and determined "the precise location of different cell types, whether they communicated with each other, and by which means." The researchers theorize that the brain's morphological layers contain different spatially localized clusters of cell types, and district subtypes executing location-specific functions. BCM's Dr. James Martin said STANN offers an "instruction manual" for scientists to analyze other brain regions or organs.
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