/* ---- Google Analytics Code Below */
Showing posts with label Organs. Show all posts
Showing posts with label Organs. Show all posts

Thursday, March 23, 2023

AI being used to cherry-pick organs for transplant

 AI being used to cherry-pick organs for transplant

By Duncan MacRae | March 2, 2023 | MarketingTech  in ArtificialIntelligence

Duncan is an award-winning editor with more than 20 years experience in journalism. Having launched his tech journalism career as editor of Arabian Computer News in Dubai, he has since edited an array of tech and digital marketing publications, including Computer Business Review, TechWeekEurope, Figaro Digital, Digit and Marketing Gazette.

A new method to assess the quality of organs for donation is set to revolutionise the transplant system – and it could help save lives and tens of millions of pounds.

The National Institute for Health and Care Research (NIHR) is contributing more than £1 million in funding to develop the new technology, which is known as Organ Quality Assessment (OrQA). It works in the same way as Artificial Intelligence-based facial recognition to evaluate the quality of an organ.

It is estimated the technology could result in up to 200 more patients receiving kidney transplants and 100 more receiving liver transplants a year in the UK.

Colin Wilson, transplant surgeon at Newcastle upon Tyne Hospitals NHS Foundation Trust and co-lead of the project, said: “Transplantation is the best treatment for patients with organ failure, but unfortunately some organs can’t be used due to concerns they won’t function properly once transplanted.

“The software we have developed ‘scores’ the quality of the organ and aims to support surgeons to assess if the organ is healthy enough to be transplanted.  “Our ultimate hope is that OrQA will result in more patients receiving life-saving transplants and enable them to lead healthier, longer lives.”

Professor Hassan Ugail, director of the Centre for Visual Computing at the University of Bradford, whose team is working on image analysis as part of the research, said: “Currently, when an organ becomes available, it is assessed by a surgical team by sight, which means, occasionally, organs will be deemed not suitable for transplant.

“We are developing a deep machine learning algorithm which will be trained using thousands of images of human organs to assess images of donor organs more effectively than what the human eye can see. “This will ultimately mean a surgeon could take a photo of the donated organ, upload it to OrQA and get an immediate answer as to how best to use the donated organ.”

There are currently nearly 7,000 patients awaiting organ transplant in the UK. An organ can only survive out of the body for a limited time. In most cases, only one journey from the donor hospital to the recipient hospital is possible. This means it is essential that the right decision is made quickly.

The project is being supported by NHS Blood and Transplant (NHSBT), Quality in Organ Donation biobank and an NIHR Blood and Transplant Research Unit to deliver research for the NHS. It also involves academics from the Universities of Oxford and New South Wales.?

Professor Derek Manas, medical director of NHSBT Organ Donation and Transplantation, said: “This is an exciting development in technological infrastructure that, once validated, will enable surgeons and transplant clinicians to make more informed decisions about organ usage and help to close the gap between those patients waiting for and those receiving lifesaving organs. We at NHSBT are extremely committed to making this exciting venture a success.”

Health Minister Neil O’Brien said: “Technology has the ability to revolutionise the way we care for people and this cutting edge technology will improve organ transplant services. Developed here in the UK, this pioneering new method could save hundreds of lives and ensure the best use of donated organs.

“I encourage everyone to register their organ donation decision. Share it with your family so your loved ones can follow your wishes and hopefully save others.”

Chief executive of the NIHR Professor, Lucy Chappell, said: “Funded by our Invention for Innovation Program, this deep machine learning algorithm aims to increase the number of liver and kidney donor organs suitable for transplantation. This is another example of how AI can enhance our healthcare system and make it more efficient. Once clinically validated and tested, cutting edge technology such as this holds the real promise of saving and improving lives.”

‘Proof of concept’ work has been carried out in liver, kidney and pancreas transplantation as well as at an advanced stage of pre-clinical testing in liver and kidney. ... '

Thursday, February 23, 2023

3D Human Printed Organs

Printing Organs to be common soon? 

3D-Printed Organs May Soon Be a Reality

By Fortune, February 17, 2023

Multilayered skin, bones, muscle structures, blood vessels, retinal tissue and even mini-organs all have been 3D printed. None are approved for human use. 

Wake Forest University scientists are 3D-printing tissues and mini-organs that mimic some of the functional properties of natural human tissues.

Progress is being made in the development of three-dimensionally (3D)-bioprinted organs, with Tal Dvir at Israel's Tel Aviv University anticipating transplantation-viable organs to become available in a decade.

Milestones to date have included Poland-based researchers’ bioprinting of a functional prototype of a pancreas that realized stable blood flow in pigs, and U.S.-based United Therapeutics’ 3D-printing of a human lung scaffold.

Stanford University's Mark Skylar Scott said, "The ability to place different cell types in precise locations to build up a complex tissue, and the capability of integrating blood vessels that can deliver the necessary oxygen and nutrients to keep cells alive, are two [3D] techniques that are revolutionizing tissue engineering."

From Fortune

View Full Article   


Monday, August 08, 2022

Ultrasound Stickers Could Continuously Image Internal Organs for Days

Remarkable scanning idea.

Ultrasound Stickers Could Continuously Image Internal Organs for Days

New Scientist, Jeremy Hsu, July 28, 2022

Xuanhe Zhao and colleagues at the Massachusetts Institute of Technology have developed a wearable ultrasound sticker that can image the wearer's internal organs continuously for 48 hours. The researchers integrated a transducer that generates and detects ultrasound waves with a patch combining hydrogel to transmit the waves, and flexible elastomer material. The researchers stuck the stickers to volunteers who performed various actions, and were able to image changes in the size and shape of their organs during those activities. The stickers currently have to be connected by wires to a computer, which translates the ultrasound waves into images and collects the data.... ' 

Sunday, July 29, 2012

Organs on a Chip

We worked for some time with this kind of bio simulation capability that came from UCSD.  Their BioNome Research Center now appears to be defunct. (Can anyone provide some information on that?) The object was to understand as early as possible what the effects of alternative pharmaceuticals might be. Now more ambitious plans at Harvard.