Widely Available AI Could Have Deadly Consequences

Misuses of Drug Discovery

ACM NEWS

Widely Available AI Could Have Deadly Consequences,     By Wired, May 18, 2022

In September 2021, scientists Sean Ekins and Fabio Urbina were working on an experiment they had named the "Dr. Evil project." The Swiss government's Spiez laboratory had asked them to find out what would happen if their AI drug discovery platform, MegaSyn, fell into the wrong hands.

In much the way undergraduate chemistry students play with ball-and-stick model sets to learn how different chemical elements interact to form molecular compounds, Ekins and his team at Collaborations Pharmaceuticals used publicly available databases containing the molecular structures and bioactivity data of millions of molecules to teach MegaSyn how to generate new compounds with pharmaceutical potential. The plan was to use it to accelerate the drug discovery process for rare and neglected diseases. The best drugs are ones with high specificity—acting only on desired or targeted cells or neuroreceptors, for instance—and low toxicity to reduce ill effects.

Normally, MegaSyn would be programmed to generate the most specific and least toxic molecules. Instead, Ekins and Urbina programmed it to generate VX, an odorless and tasteless nerve agent and one of the most toxic and fast-acting human-made chemical warfare agents known today.

From Wired

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Thoughtful Piece, Dangers of AI

Useful caurions we need to think about and will soon become important contexts of these methods.

 AI’s 6 Worst-Case Scenarios Who needs Terminators when you have precision clickbait and ultra-deepfakes? By NATASHA BAJEMA  in IEEE Spectrum

HOLLYWOOD’S WORST-CASE scenario involving artificial intelligence (AI) is familiar as a blockbuster sci-fi film: Machines acquire humanlike intelligence, achieving sentience, and inevitably turn into evil overlords that attempt to destroy the human race. This narrative capitalizes on our innate fear of technology, a reflection of the profound change that often accompanies new technological developments.

However, as Malcolm Murdock, machine-learning engineer and author of the 2019 novel The Quantum Price, puts it, “AI doesn’t have to be sentient to kill us all. There are plenty of other scenarios that will wipe us out before sentient AI becomes a problem.”

“We are entering dangerous and uncharted territory with the rise of surveillance and tracking through data, and we have almost no understanding of the potential implications.”

—Andrew Lohn, Georgetown University

In interviews with AI experts, IEEE Spectrum has uncovered six real-world AI worst-case scenarios that are far more mundane than those depicted in the movies. But they’re no less dystopian. And most don’t require a malevolent dictator to bring them to full fruition. Rather, they could simply happen by default, unfolding organically—that is, if nothing is done to stop them. To prevent these worst-case scenarios, we must abandon our pop-culture notions of AI and get serious about its unintended consequences.    

1. When Fiction Defines Our Reality… (continued in article)