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Showing posts with label Cardio. Show all posts
Showing posts with label Cardio. Show all posts

Friday, February 24, 2023

3D Heart Replica

Uses include individual study, for diagnosis and planning care.

3D-Printed Heart Replicas Look, Pump Like the Real Thing, By MIT News, February 24, 2023

A doctor holds a custom-made robotic heart.

MIT engineers are hoping to help doctors tailor treatments to patients’ specific heart form and function, with a custom robotic heart. Physicists at the Massachusetts Institute of Technology (MIT) led a team that developed a procedure to enable the creation of three-dimensionally (3D) printed replicas of patients’ hearts.

After converting medical images of a patient's heart into a 3D computer model, the researchers used a polymer-based ink to 3D-print a flexible shell identical to the patient's heart.

The researchers developed sleeves that may be wrapped around a 3D-printed heart and aorta to replicate a patient's blood-pumping ability.  Said graduate student Luca Rosalia, "The advantage of our system is that we can recreate not just the form of a patient's heart, but also its function in both physiology and disease."

From MIT News

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Thursday, September 08, 2022

Pacemaker That Dissolves

Interesting solution 

Pacemaker Diss0lves

No More Invasive Surgery—This Pacemaker Dissolves Instead Temporary pacemakers are often vital but dangerous to remove when their jobs are done  ..    By JOANNA GOODRICH,   Spectrum IEEE

After having cardiovascular surgery, many patients require a temporary pacemaker to help stabilize their heart rate. The device consists of a pulse generator, one or more insulated wires, and an electrode at the end of each wire.

The pulse generator—a metal case that contains electronic circuitry with a small computer and a battery—regulates the impulses sent to the heart. The wire is connected to the pulse generator on one end while the electrode is placed inside one of the heart’s chambers.

But there are several issues with temporary pacemakers: The generator limits the patient’s mobility, and the wires must be surgically removed, which can cause complications such as infection, dislodgment, torn or damaged tissues, bleeding, and blood clots.

Researchers have found that a dissolving pacemaker can make a real difference for patients. Last year a team of scientists at Northwestern University, in Evanston, Ill., developed such a device, which will allow patients to live without being tethered to external hardware. The dissolving pacemaker is 250 micrometers thick, weighs less than half a gram, and dissolves in the patient’s body, eliminating the need for surgical removal.

In May, the researchers introduced an upgraded, smart version of the pacemaker. It connects to a network of soft, flexible wearable sensors developed by the team. These sensors monitor various physiological functions to help determine when to pace the heart and at what rate. The pacing system is completely autonomous.

The device also releases an anti-inflammatory drug while it dissolves.

“When you implant any kind of foreign hardware into the human body, cells attack that object,” explains Igor Efimov, a member of the development team and a professor of biomedical engineering at the university. He says that releasing the anti-inflammatory drug will stop the body from rejecting the pacemaker.   .... 

Wednesday, January 27, 2021

Cardiovascular Disease: Improving Therapy with Digital Twins

 Digital twins for modeling therapy. 

An integration of a number of modeling methods are brought together with imaging.  

Cardiovascular Diseases: Computer Model Improves Therapy

Graz University of Technology (Austria), Christoph Pelzl, January 22, 2021

Researchers at Austria's University of Graz and the Graz University of Technology (TU Graz) have generated digital twins of human hearts, which doctors can use to pre-model optimal therapies and improve the likelihood of successful treatment for cardiovascular diseases. Imaging algorithms construct a digital twin from diagnostic data, which provides information to help understand the individual clinical situation and consider various therapeutic scenarios. TU Graz's Thomas Pock said computerized heartbeat simulation requires calculating millions of factors, and demands "complex mathematical procedures, special algorithms, and special hardware that can perform billions of computing actions per second." The new technique can routinely produce anatomically accurate digital twins of patient hearts in clinical environments.  ... '